Short answer, yes, long answer, mostly. If you dig back into the really early Requiem supplements the tone is a bit different. It's coming fresh off Masquerade and doesn't want to rock the boat too much, but it's also trying hard not to just be Masquerade 2.0, so much of the oldest material is stuck between those two impulses. Once you hit Damnation City and Requiem for Rome (which was kind of a soft reboot of the line anyway), the difference between first edition and second edition is more academic, apart from rules. I'd argue there are bigger tonal changes within the first edition than between...