- The less you reference the real world, the better. Run your campaign in a fictional city (or town even), in an ambiguous time period, in an unmentioned country. Strive for something like the vibe of Gotham City in the 90s Batman animated series.

- Vampire vs vampire is boring. Vampire vs humans is where the most fun and drama is. The Second Inquisition is the right idea even if I'm extremely skeptical of 5th ed.

- Lupines, mages, and fairies are unnecessary in V:TM and detract from almost all of its themes. They are fine in their own games.

- Fewer players...