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[Mister_Dunpeal]

The WoD sorcerer stuff might actually be more powerful than blood magic in some ways (compare hellfire with Lure of flames) so I could see reasons not to do so. And while some 'in game' characters (like mages) can be simulated with disciplines I do think this detracts from the 'uniqueness' of vampires if you let humans access the exact same abilities (some of the books have depicted the disciplines both as blessings AND curses... potence isn't just about raw strength but also brutality and savagery.) Its still possible (the psychic stuff in Hunters Hunted II are modeled on certain disciplines...

[Mister_Dunpeal]

I don't care to get into the specifics (IE Trump), but when it comes to the supernatural influence on the natural, consider it from a view of balance and imbalance. When things are in balance there is harmony and little excess. When things are unbalanced... you can get excesses of one form or another. Stuff like inequalities, discrimination, etc. are just another set of symptoms of some larger/deeper cause just as there can be supernatural signs of that imbalance.

As to how you address it, that depends on the game system. In Mage, for example reality is shaped greatly by the...

[Mister_Dunpeal]

Oh and Werewolf is obviously big on 'balance' issues too, so there's all kinds of themes you can link to there...