Not necessarily a bad thing, but I admit I'm biased because the game I've used the Nameless in is absolutely a crossover.
I've shaken things up a little, where the "Cross" the Nameless refers to is actually an abyssal Crossways, and the Nameless itself is a group of supernaturals led by an elder of VII, which in this interpretation is a strix that has been subsumed by the God Machine.

Glad to see this thread still going. The Nameless is definitely one of my favorite scenarios to play with....