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The counter to Dominate is a catering staff of Ghouls with orders to slap the vampire if they think he’s been dominated, also video conferencing with a closed system connection.

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First thing I would do is check everyone was on board with continuing since some players might feel that the story had reached a satisfactory conclusion, after that I would have gone through what npcs might intervene and everything I had going on behind the senes to come up with an out.
I assume you did something similar, worst case scenario have something like TFV recruit them.

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It took some finding but we’ve had a similar question although this one seems to be doing better.
http://forum.theonyxpath.com/forum/m...e-specifically
Should have something relevant.

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You’re right CofD is a narrative system which is why so many merits are per game rather than per day or month, I’m all for simulationist systems but this isn’t one. Balance comes from police investigations into all those dead people and the fact that someone else could have taken Allies to have those 3 people trying to kill you in the first place. Combat is dangerous to discourage it so you have a reason to explore other options.

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If each house is one clan only then the Dynasty Membership merit is sufficient for your needs, beyond that depends on what they get from being in charge of the whole thing (and how many steps there are between 3 dots in DM and the top job).
As I mentioned above I would be tempted to write up a Mystery Cult to represent the cooperation between the different houses maybe requiring 3 dots in Dynasty Membership before you can join it but you could have a merit for wider status in the whole Vennic Dynasty but if you do that it’s probably best to start your players off with one free dot in clan...

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You could treat the Dynasty as effectively another covenant or make a Mystery Cult to represent it. Remember that if something is unavailable to the players like being the founder then there’s no reason to try and balance it or make it a merit so some of your concerns might be redundant.

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The Invictus have a practice of leaving everything to someone else when you face torpor and then when you wake up you share everything they have and look after their stuff when they torpor, such relationships usually top out at 3 members. The Dynasty Membership merit in the core book is intended for single clan membership since it requires Clan Status to take it.
Now that’s out of the way it should be relatively easy to rework anything you need to to make this work for your game, what would you want to represent with the merits?

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Supernatural damage isn’t downgraded so they would naturally do lethal damage but the only two disciplines that do lethal damage have it at the forth dot as a +2 weapon for a scene or the fifth dot also giving the Broken condition and possibly reducing Composure so I still feel it’s a bit on the strong side unless you intend for the acid to be mundane damage.
What boon and bane are you going to give the bloodline?
Also the ability to remove Conditions is incredibly powerful basically allowing an opt out from most attempts to use disciplines on the character and as written Amnesia,...

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Honestly they should have an explanation ready to go before they committed to going but since the premise of the plot is that they go and the killings are an unaccounted for veritable it’s understandable that whatever they planned didn’t work out.

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I’d have to check but I don’t think there’s anything else that can reduce Resistance, I think you’ve made it too powerful even if it wasn’t the first dot. On a related note usually the first dot isn’t that powerful, maybe switch the first two round so the first dot is more passive before getting to the good stuff.

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Or poach Revenants that others have made....

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Mekhet find the killer, Gangrel go get the cops or at least find out what’s going to stop the people who try.
Honestly this would probably work better if the players were Ghouls.